Is Tongkat Ali clinically proven?

Is tongkat ali clinically proven?

Although it is a relatively unknown supplement in most parts of the world, tongkat ali it is one of the most well studied and established supplements to increase testosterone in men. Here are a couple of studies to give you a taste.

British Journal of Sports Medicine

2003
THE ERGOGENIC EFFECTS OF EURYCOMA LONGIFOLIA JACK: A PILOT STUDY

Eurycoma longifolia Jack (ELJ), which contains quassinoids such as eurycomalacton, eurycomanon, and eurycomanol, has been reported to have aphrodisiac properties and to increase testosterone levels in men. Previous studies have established that the testosterone supplementation increases fat free mass, muscle strength, and muscle mass, which are important for physical function and athletic performance.  {…}. The treatment produced 2.92% greater reduction in electrical activity of the muscle measured at the end of the experiment compared with placebo. The mean arm circumference of the treatment group increased significantly by 1.8 cm after the supplementation, from 30.87 (1.88) to 32.67 (1.96) cm (p = 0.011), but there was no significant increase in the placebo group. The results suggest that water soluble extract of Eurycoma longifolia Jack increased fat free mass, reduced body fat, and increased muscle strength and size, and thus may have an ergogenic effect. Further investigations are warranted.

Phytotherapy Research

2013 , June 11
TONGKAT ALI AS A POTENTIAL HERBAL SUPPLEMENT FOR PHYSICALLY ACTIVE MALE AND FEMALE SENIORS-A PILOT STUDY

Tongkat Ali (Eurycoma longifolia; TA) is known to increase testosterone levels and alleviate aging males’ symptoms. This study aimed at investigating TA as an ergogenic supplement for elderly people. Thirteen physically active male and 12 physically active female seniors (57-72 years) were supplemented with 400-mg TA extract daily for 5 weeks. Standard hematological parameters were taken. {…}. Treatment resulted in significant increases in total and free testosterone concentrations and muscular force in men and women. The increase in free testosterone in women is thought to be due to the significant decline in sex hormone-binding globulin concentrations. The study affirms the ergogenic benefit of TA through enhanced muscle strength.

References:

  1. Ang HH, Lee KL, Kiyoshi M. Eurycoma longifolia Jack enhances sexual motivation in middle-aged male mice. J Basic Clin Physiol Pharmacol. 2003;14(3):301-8.
  2. Ang HH, Sim MK. Eurycoma longifolia Jack enhances libido in sexually experienced male rats. Exp Anim. 1997 Oct;46(4):287-90.
  3. Ang HH, Ngai TH, Tan TH. Effects of Eurycoma longifolia Jack on sexual qualities in middle aged male rats. Phytomedicine. 2003;10(6-7):590-3.
  4. Frydrychová S, Opletal L, Macáková K, Lustyková A, Rozkot M, Lipenský J. Effects of herbal preparation on libido and semen quality in boars. Reprod Domest Anim. 2011 Aug;46(4):573-8. doi: 10.1111/j.1439-0531.2010.01703.x. Epub 2010 Nov 23.
  5. Ang HH, Cheang HS. Effects of Eurycoma longifolia jack on laevator ani muscle in both uncastrated and testosterone-stimulated castrated intact male rats. Arch Pharm Res. 2001 Oct;24(5):437-40.
  6. Zanoli P, Zavatti M, Montanari C, Baraldi M. Influence of Eurycoma longifolia on the copulatory activity of sexually sluggish and impotent male rats. J Ethnopharmacol. 2009 Nov 12;126(2):308-13. doi: 10.1016/j.jep.2009.08.021. Epub 2009 Aug 22.
  7. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia. 2012 May;44 Suppl 1:226-30. doi: 10.1111/j.1439-0272.2011.01168.x. Epub 2011 Jun 15.
  8. Ismail SB, Wan Mohammad WM, George A, Nik Hussain NH, Musthapa Kamal ZM, Liske E. Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men. Evid Based Complement Alternat Med. 2012;2012:429268. doi: 10.1155/2012/429268. Epub 2012 Nov 1.
  9. Chan KL, Low BS, Teh CH, Das PK. The effect of Eurycoma longifolia on sperm quality of male rats. Nat Prod Commun. 2009 Oct;4(10):1331-6.
  10. Tambi MI, Imran MK. Eurycoma longifolia Jack in managing idiopathic male infertility. Asian J Androl. 2010 May;12(3):376-80. doi: 10.1038/aja.2010.7. Epub 2010 Mar 29.
  11. G Jackson, S Arver, I Banks, and V J Stecher. Counterfeit phosphodiesterase type 5 inhibitors pose significant safety risks. Int J Clin Pract. 2010 March; 64(4): 497–504.
  12. Ang HH, Lee KL. Contamination of mercury in tongkat Ali hitam herbal preparations. Food Chem Toxicol. 2006 Aug;44(8):1245-50. Epub 2006 Mar 29.

Independent Studies

In 2003 Tongkat Ali was clinically tested against a placebo and came back with impressive results, the effects of Eurycoma Longifolia Jack documented in the British Journal of Sports Medicine (Article Number 007) The tests show a significant increase in testosterone levels over a 12 week period of usage compared to those using the placebo.

This resulted in the candidates that took the Tongkat Ali having a greater increase in fat-free mass at the end of the trial.

Other Tests on Tongkat Ali

Testosterone levels 4 weeks from finishing the first 8 week cycle.

Testosterone levels 8 weeks into the second of 2 cycles.

Reverse side of the results pages showing standard levels for all age ranges and gender.

Summary

Tongkat Ali is a natural testosterone booster that works in a safe and unique way to increase the natural production of testosterone. It has positive results like reversing the effects of Erectile Dysfunction and increasing the ability to burn body fat and muscle mass increasing.

Tongkat Ali and Testosterone

Tongkat ali root have long been used aphrodisiac and remedy for the age related sexual disorders. It was also used to cure the symptoms of Andropause. The roots of the plant have shown to increase libido in men, promote semen quality as well as support muscular growth. These effects have largely been attributed to increases in testosterone.

In year 2012, a study on Malaysia consisting of 76 men, only 35% of whom has normal level of testosterone were tested. After a month of supplementing with Tongkat Ali, the number of men in group with the normal hormone level jumped to over 90%.

A separate double-blind, placebo-controlled study found that men who consumed tongkat ali on a daily basis experienced improvements in erectile function, libido, and semen volume. Some even experienced fat loss. [8]

Tongkat Ali and Male Fertility

Although, not everyone who is consuming Tongkat Ali wants to increase libido and fertility yet it is worth mentioning that it supports and promotes normal sperm quality which can be measured by volume, motility, concentration and impacts the fertility in males.

In one study, 75 men that were consuming Tongkat Ali everyday observed and experienced significant improvement in their sperm quality and the improvement lasted for several months after the study. Almost 15% of the participants even reported new pregnancies. [10]

Maca Research and Credibility

Researches

1) Maca Enhances Sexual Function and Drive
With 12 weeks supplementation of Maca extract, a research (DB-RCT) of 50 men with mild erectile dysfunction shows improvement in erectile function and sexual well-being.
Another research (DB-RCT) of 14 healthy postmenopausal women, 6 weeks of maca consumption lowerd sexual dysfunction
In a research of 9 men, Black maca improves their sperm count, volume, motility, and quality.

2) Maca Reduces Blood Pressure
In research of 50 people, researchers observed that Maca consumption was linked with reducing blood pressure.
In another research (DB-RCT) of 29 postmenopausal women, 6 weeks of maca consumption resulted in reduced blood pressure

3) Maca Enhance Quality of Life
In a research (DB-RCT) of 197 adults, red and black maca improved quality of life (in aspect of health related area).
in a research of 50 adults living at high altitude, Maca supplementation improved quality of life (in aspect of health related area).

4) Maca Relieves Osteoarthritis Symptoms
In a research (DB-RCT) of 95 osteoarthritis patients, Reparagen, a compound consist of 83% maca, is found to relieve symptoms such as pain, stiffness, and other physical function

5) Maca Increases Bone Density
In a pilot research (DB-RCT) of 12 menopausal women, maca gradually improves bone density over a period of 4 months.
In a research using mice, Maca also stops bone loss due to decreasing reduced estrogen levels

6) Maca Lowers Inflammation and Oxidative Stress
Black maca lowers level of oxidative stress in mice
In a research of 50 people, those who regularly supplement maca maintain reduced levels of inflammation (IL-6) as compared to those who did not [R].

7) Maca Stabalizes Female Sex Hormones
In a research (DB-RCT) of 20 postmenopausal women, regular consumption of Maca powder for 2 months reduced follicle stimulating hormone and luteinizing hormone, and improved level of estrogen and progesterone.

8) Maca Lowers Levels of Blood Sugar
In a research (DB-RCT) of 197 adults, Black maca lowered level of blood glucose

9) Maca Relieves Chronic Mountain Sickness
Chronic mountain sickness is due to abnormally low oxygen level due to high altitude.
In a research on adults, maca supplementation reduces the symptoms of chronic mountain sickness.
In a research (DB-RCT) of 197 adults, red maca reduced symptoms of chronic mountain sickness

10) Maca Can Enhance Cognitive/Learning Function
Maca enhances learning capacity in mice research, with black maca displaying the best effects
Black maca also prevent memory deterioration in mice

11) Maca Can Shield Skin from UV Exposure
Maca extract administered onto mice’ skin show sign of shielding effect from UV radiation
Red, black, and yellow maca administered to the mice’ skin also prohibit growth of sunburn cells and other symptoms of UV damage, as well as displaying signs of antioxidant effects

Panax Ginseng Research and Credibility

Panax Ginseng Research and Credibility

Topo, E., Soricelli, A., D’Aniello, A., Ronsini, S., & D’Aniello, G. (2009). The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Reproductive Biology and Endocrinology, 7(120), 1482-1488.Willoughby, D. S., & Leutholtz, B. (2013). D-Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men. Nutrition Research, 33(10), 803-810.
Poole, C., Bushey, B., Foster, C., Campbell, B., Willoughby, D., Kreider, R., … & Wilborn, C. (2010). The effects of a commercially available botanical supplement on strength, body composition, power output, and hormonal profiles in resistance-trained males. Journal of the International Society of Sports Nutrition, 7(1), 34.
Wilborn, C. D., Kerksick, C. M., Campbell, B. I., Taylor, L. W., Marcello, B. M., Rasmussen, C. J., … & Kreider, R. B. (2004). Effects of zinc magnesium aspartate (ZMA) supplementation on training adaptations and markers of anabolism and catabolism. Journal of the International Society of Sports Nutrition, 1(2), 12-20.
Brilla, L. R., & Conte, V. (2000). Effects of a novel zinc-magnesium formulation on hormones and strength. Journal of Exercise Physiology Online, 3(4), 26-36.
Simão, R., Leite, R. D., Speretta, G. F. F., Maior, A. S., De Salles, B. F., de Souza Junior, T. P., … & Willardson, J. M. (2013). Influence of upper-body exercise order on hormonal responses in trained men. Applied Physiology, Nutrition, and Metabolism, 38(2), 177-181.
Kraemer, W. J., Marchitelli, L., Gordon, S. E., Harman, E., Dziados, J. E., Mello, R., & Fleck, S. J. (1990). Hormonal and growth factor responses to heavy resistance exercise protocols. Journal of Applied Physiology, 69(4), 1442-1450.